Guanidinium hydrochloride ≥99%, white crystalline powder for molecular biology

Supplier: MP BIOMEDICALS (FKA ICN BIOMED
Warning

Synonyms: Guanadine hydrochloride, Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidine HCI, Guanidine chloride, Guanidinium chloride, Guanidine hydrochloride

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76177-760EA 134.3 USD
76177-760 76177-762 76177-764 76177-766 76177-962
Guanidinium hydrochloride ≥99%, white crystalline powder for molecular biology
Guanidinium hydrochloride

Storage: Room Temperature
Guanidine hydrochloride consists of a network of guanidinium cations and chloride anions linked by N–H•••Cl hydrogen bonds, it is a strong chaotropic agent. Guanidine HCl may agglomerate upon storage. It may appear as a free-flowing crystalline powder, a free flowing powder with solid material dispersed throughout, or a solid. The quality of the product does not appear to be affected and solutions prepared from the free-flowing and lumpy guanidine HCl appear identical.
Guanidine hydrochloride can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Also used in the isolation of RNA. Guanidine hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of protein, it can solubilize insoluble or denatured proteins such as inclusion bodies and be used for the recovery of periplasmic proteins.


  • Molecular Biology Reagent Grade
  • Presentation: White Crystalline Powder

Formula: NH₂C(=NH)NH₂·HCl
Melting Pt: 180…190 °C
Density: 1.345 g/cm³ (20 °C) (lit.)
Storage Temperature: Ambient
MDL Number: MFCD00013026
CAS Number: 50-01-1
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Specification Test Results

Identity Test Passes
Purity ≥99%
Melting Point 180 - 190°C
FTIR Conforms to Standard
pH (6.0 M aq soln) 4-6
OD260 (6.0 M aq soln) ≤0.03
Loss on Drying ≤1.0%
Solubility (6.0 M aq soln) Clear, Colorless Solution


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