Zeta Plus™ ZB Series Filter Cartridges are optimized for clarification of pharmaceutical, biological, bioprocess and cosmetic fluids, in addition to, providing protection of downstream sterilizing grade membrane filters. The strong positive charge provides enhanced reduction of negatively charged contaminants compared to a mechanical filtration mechanism alone.
- Zeta Plus™ ZB Series Filter Cartridges are pharmaceutical-grade filters that exhibit a positive charge and provide economical filtration and reliable particle reduction
- Zeta Plus ZB series filter cartridges retain contaminants by both mechanical entrapment and electrokinetic adsorption
- FDA Drug Master File supports regulatory submissions
- Zeta Plus ZB series filter cartridge media is offered in a full range of scalable capsule and cartridge filter configurations, enabling pilot testing and scale-up using the same media construction as in full-scale systems
- Zeta Plus construction
- Accentuating the positive
As we manufacture Zeta Plus™ ZB Series filter media, we use a charged resin system to bind a positive charge to the filter matrix, permanently forming an interconnected filtration structure with positively charged electrokinetic capture sites. The resulting porous depth filter is a complex network of charge-enhanced flow channels capable of removing bacteria, particulate, cellular debris and submicron contaminants like DNA to a level that mechanical screening alone cannot attain. Zeta Plus™ ZB Series Filter Cartridges can protect downstream membranes, thereby extending filter life and reducing overall filtration costs.
Our family of Zeta Plus™ ZB series filter cartridges are composed of advanced cellulose-based depth filtration media, designed to retain contaminants by both mechanical entrapment and electrokinetic adsorption. Zeta Plus filter media is composed of high surface area filter aids embedded in a cellulose fiber matrix. During the manufacturing process, the ZB resin system incorporated into the filter media imparts a strong positive charge to the filter matrix to permanently form an interconnected filtration structure with positively charged electrokinetic capture sites. The resulting porous depth filter is a complex network of charge-enhanced flow channels capable of removing bacteria, particulate, cellular debris and submicron contaminants to a level which mechanical screening alone cannot achieve.
Zeta Plus Applications include Pharmaceuticals, Blood and Blood Products, Antibiotics, Cough Syrups, Intravenous Solutions, Vaccines, Growth Media, Bioprocess Fluids (bacteria and yeast cell lysates, cell separation) and Protection of downstream processes including membrane filters and chromatography columns.
Zeta Plus ZB series filter media is available in a broad range of micron ratings to meet clarification applications. Optimum flow rates vary by application, but in general, lower flux rates often result in longer service life, greater throughputs and superior system economics.
Zeta Plus Scalability.
We also offer a range of cartridge sizes, making scale-up easy and predictable, from laboratory scale to pilot plant, and from pilot plant to full production. Filter cartridges are available in 8", 12" and 16" diameters, with surface areas ranging from 650 cm² to 3.9 m² per cartridge to make scale-up straight forward and predictable.
Regulatory Support
We support all Zeta Plus™ ZB Series Filter Cartridges with a Regulatory Support File and Certificate of Quality to support your validation and regulatory submissions. The products are also documented in a Drug Master File (DMF) on record with the US Food and Drug Administration (FDA).
With a range of cartridge sizes, quality tested media and support documentation, Zeta Plus™ ZB Series Filter Cartridges are an ideal choice for many pharmaceutical and biological filtration processes.
