1,2-Diheptanoyl-sn-glycero-3-phosphocholine ≥99%, Powder
Supplier: AVANTI POLAR LIPIDS INC MS
Synonyms:
2-[[(2R)-2,3-diheptanoyloxypropoxy]-oxido-phosphoryl]oxyethyl-trimethyl-azanium
, DHPC
, Diheptanoyllecithin
, L-alpha-Diheptanoyllecithin
DHPC preserves the native conformation and therefore the activity of the solubilized proteins. The three dimensional structure and activity of proteins are retained not only at the 10-15mM DHPC concentrations at which maximum solubilization usually occurs, but also over a large range of DHPC concentrations (up to 40mM).
- Purified by HPLC
- Special precautions are taken to protect the products for oxidization and hydrolysis
Not only is the three dimensional structure and hence the activity of most protein retained in excess DHPC, but the proteins also appear to be stable in DHPC. Such a result suggests that the direct interaction of DHPC with integral membrane proteins is weak. If the interaction of DHPC with membrane proteins is indeed weak, it follows that intrinsic membrane lipids will remain associated with the membrane proteins.
Formula:
C₂₂H₄₄NO₈P MW: 481.56 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00063532 CAS Number: 39036-04-9 |
Specification Test Results
Chloroform solution | Clear solution with no foreign matter |
TLC purity |
|
TLC Ninhydrin | Negative |
TLC Iodine | One major spot |
DMAP / UV-VIS | Absence of DMAP |
FAME (GC/FID) | NLT 99% 07:0 (AUC) |
Mass Spectroscopy | [M+H]+ = 482.560 ± 1 amu |
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