Primarily designed for the demanding needs of cryosectioning in biomedical, neuro-anatomical and pharmaceutical research.
- Freestanding, motorized open-top cryostat with independent specimen temperature control
- Spacious, easy-to-clean cryochamber with illumination
- Removable heated glass sliding window.
Cryochamber temperature setting down to 40°C in 1° steps. Permanently cooled (down to -45 °C) quick-freeze shelf for 10 specimen discs. Programmable automatic 24-hour defrost cycle. Defrost cycle duration programmable from 6 to 12 minutes. Additional manual defrost feature. Microprocessor-controlled. Foil-protected control panel with locking key to prevent inadvertent changes of programmed parameters. Menu-driven operation in 5 languages (German, English, French, Spanish, Italian) via LCD display. Counterbalanced handwheel, lockable in two positions, for manual sectioning. Locking status indicated on display.
Motorized sectioning: Motorized sectioning operated via control panel and foot switch. Section counter with reset. Sectioning window adjustment. Handle of the handwheel can be centered in motorized operation. Emergency stop switch. 3 sectioning modes: intermittent, single and continuous stroke. 2 sectioning speed ranges selectable: 0.1 - 170 mm/s; 0.1 - 100 mm/s. Additional maximum speed setting of: 210 mm/s.
Specimen temperature control: Specimen head with specimen temperature control. Temperature setting range: -10 °C to -50 °C in 1° increments. Specimen quick-freeze feature. Manual defrosting. Stainless steel rotary microtome (all specifications related to temperature are valid for a room temperature up to 22 °C and a relative air humidity of 60%).
Section thickness range: 0.5 to 300 µm, in 0.5 µm increments from 0.5 to 2 µm, in 1 µm increments from 2 to 10 µm, in 2 µm increments from 10 to 20 µm, in 5 µm increments from 20 to 60 µm, in 10 µm increments from 60 to 100 µm, in 50 µm increments from 100 to 300 µm, X/Y/Z specimen precision orientation of 8°. Specimen retraction: 50 µm Total horizontal specimen feed: approx. 25 mm Total vertical stroke: approx. 60 mm. Programmable trimming: 5 - 150 µm, selectable in 6 discrete steps, in 5, 10, 30, 50, 100 and 150 µm increments. Motorized coarse feed: 500 µm/s and 1000 µm/s.
It is the instrument of choice for all research applications and for advanced clinical cryosectioning needs.
Particularly when working in biomedical, neuro-anatomical and pharmaceutical research with delicate specimens – for example brain samples in neuroscience – the precise specimen orientation and the specimen feed system guarantees reproducible, thin, serial sections of maximum quality.
Certifications: Admissions: CE, UL, c-UL, VDE.
Ordering information: Standard delivery includes 1 Cryostat with microtome (14 0470 33518); 1 Handwheel with marking, antibacterial (14 0443 36660); 1 Heat extractor, stationary (14 0369 11197); 1 Low-temperature stabilizer for heat; extractor (14 0452 27919); 1 90° prism for direct specimen freezing on specimen head with clamping screw to facilitate specimen trimming (14 0443 25949); 1 Set of specimen discs (14 0470 43550); 4 Specimen discs, 25 mm (14 0416 19275); 4 Specimen discs, 30 mm (14 0370 08587); 1 Storage shelf, right (14 0443 25723); 1 Storage shelf, left (14 0443 33549); 1 Section waste tray (14 0400 26817); 1 Foot switch with protective guard (14 0505 33888); 1 Rubber mat (14 0443 25732); 1 Freezing shelf cover (14 0443 30783); 1 Brush shelf (14 0398 13088); 1 Tool set (14 0436 43463); 1 Brush, fine (14 0183 28642); 1 Leica-brush with magnet (14 0183 40426); 1 Allen key, size 1.5 (14 0222 10050); 1 Allen key, size 2.5 (14 0222 04137); 1 Allen key, size 3.0 (14 0222 04138); 1 Allen key, size 4.0 (14 0222 04139); 1 Allen key with spherical head, size 4.0 (14 0222 32131); 1 Allen key, size 5.0 (14 0222 04140); 1 Allen key with handle, size 5.0 (14 0194 04760); 1 Allen key, size 6.0 (14 0222 04141); 1 Single-head wrench, size 13 (14 0330 33149); 1 Single-head wrench, size 16 (14 0330 18595); 1 Tissue freezing medium for cryosectioning, 125 ml (14 0201 08926); 1 Bottle of cryostat oil, 50 ml (14 0336 06098); 1 IFU-Bundle Leica CM3050 S (14 0443 80001); consisting of: 1 Instructions for use Leica CM3050 S, printed, DE/EN; 1 CD including available languages; 1 IFU-language order.
