EGTA (ethylene glycol bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid) ≥97% for molecular biology
Supplier: MP BIOMEDICALS (FKA ICN BIOMED
Synonyms:
Ethylenebis(oxyethylenenitrilo)tetra(acetic acid)
Physical Appearance: White Powder
pKa: < 2, 2.7, 8.8, and 9.5 (Lit.)
Solubility: Soluble in alkaline solutions (1 g in 10 mL 1 N NaOH + 50 mL water-clear, colorless solution).
Typical Working Concentration: as a metalloprotease inhibitor (effective concentration is typically 1 to 10 µM)
Ethylene Glycol-bis-(beta-aminoethylether)-N,N,N',N'-tetraacetic Acid is a chelating agent. It is an inhibitor of alkaline phosphatase activity which is useful in ELISA reactions.
Ethylene Glycol-bis-(beta-aminoethylether)-N,N,N',N'-tetraacetic Acid is a chelating agent for determination of calcium in the presence of magnesium; it can also detect cadmium in the presence of zinc. It is also useful for the removal of heavy metal ions in biological systems. It is shown to activate Ca2+- stimulated ATPase in rat liver plasma membranes and induce apoptosis in PC12 cells. It also inhibits the zinc-dependent endopeptidases, matrix metalloproteinases.
Formula:
C₁₄H₂₄N₂O₁₀ MW: 380.35 g/mol Melting Pt: 235…245 °C Storage Temperature: Ambient |
MDL Number:
MFCD00004291 CAS Number: 67-42-5 EINECS: 200-651-2 |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...