4-(4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl)-6-ethylresorcinol ≥90% (by HPLC), Calbiochem®, Sigma-Aldrich®

Supplier: MilliporeSigma

Synonyms: HSP90 Inhibitor , CCT018159

M-Clarity™ quality level = MQ100

385920-5MG

82603-948EA 245.87 USD

82603-948

4-(4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl)-6-ethylresorcinol ≥90% (by HPLC), Calbiochem®, Sigma-Aldrich®

4-(4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl)-6-ethylresorcinol

A cell-permeable pyrazoloresorcinol compound that inhibits HSP90 ATPase activity against human HSP90β and yeast HSP90.

Targets the enzyme's N-terminal ATP binding site
Exhibits no detectable effects against human Hsp70 or topoisomerase II even at concentrations as high as 100 µM
Inhibits a panel of 20 commonly studied kinases at higher concentrations

Formula: C₂₀H₂₀N₂O₄
MW: 352.38 g/mol
Storage Temperature: Freezer

CAS Number: 171009-07-7

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