Pierce® Pegylation Reagents, Methyl-PEG-Thiol Compound, Thermo Scientific

Supplier: Thermo Fisher Scientific
Pierce® Pierce™
26132 26132
PI26132EA 422.58 USD
CAPI26132 PI26132
Pierce® Pegylation Reagents, Methyl-PEG-Thiol Compound, Thermo Scientific
Protein Purification Protein Purification Reagents
Methyl-PEG4-thiol is a methyl- and sulfhydryl-terminated compound that contains a 4-unit polyethylene glycol (PEG) spacer and is used to modify surfaces such as quantum dots, monolayers and magnetic particles.

  • PEG groups are flexible, non-immunogenic and hydrophilic
  • Terminal monodentate thiol reacts spontaneously with gold surfaces through dative binding
  • Terminal methyl group coats quantum dot and other surfaces to reduce nonspecific binding in assays

The use of MT(PEG)4 with CT(PEG)12 in surface modification can form a hydrophilic 'lawn' of methyl ether-terminated PEGs with periodic exposed carboxylic acid-containing PEGs. The exposed carboxylic acid groups can be coupled to affinity ligands using the carbodiimide coupling reaction with EDC and sulfo-NHS.

Caution: For Research Use Only. Not for use in diagnostic procedures.
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