Ru360, Calbiochem®
Supplier: MilliporeSigma
Packaged under inert gas.
557440-500UG
557440-1SET
80054-328EA
426.29
USD
80054-328
80109-780
Ru360, Calbiochem®
Ru360
Ru360 is a cell-permeable oxygen-bridged dinuclear ruthenium amine complex.
- Mitochondrial Function Inhibtor
This binds to mitochondria with high affinity (Kd = 340 pM) and blocks Ca2+ uptake into mitochondria in vitro (IC₅₀ = 184 pM). This does not affect other cellular Ca2+ transport processes involved in cardiac muscle contraction, even at micromolar levels.
Special Instructions: Unstable in solution; reconstitute just prior to use.
Specification Test Results
Primary Target | Ca2+ uptake into mitochondria in vitro |
Primary Target IC50 | 184 pM blocking Ca2+ uptake into mitochondria in vitro; and in situ in intact myocytes; Kd = 340 pM for binding mitochondria |
Purity | ≥97% by capillary electrophoresis |
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