Anti-BATF Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemicals

600-401-Z35

10802-014EA 518 USD

10802-014

Anti-BATF Rabbit Polyclonal Antibody

Antibodies

BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination.

Recommended Dilutions: ELISA: 1:5,000; Immunofluorescence Microscopy: 20 µg/mL; Western Blot: 0.5 ?g/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: BATF
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: N-Terminal
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat

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