Tunicamycin 95%
Supplier: Thermo Scientific Chemicals
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Danger
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A mixture of homologous nucleoside antibiotics
- Moisture and light sensitive
Tunicamycin has been widely used in the study of glycoprotein synthesis in various biological systems. During protein glycosylation, tunicamycin is noted to be an inhibitor of the transfer of saccharide moieties to dolichol during dolichol-linked glycoprotein synthesis
Additionally, tunicamycin has been reported to prevent cell cycle progression in primary cultures of rat glial cells, as well as inhibit lipid-mediated protein glycosylation in chick or mouse fibroblasts in a dose-dependent manner.
Dose-dependent inhibition of DNA synthesis may be related to the alteration of glycoproteins, which thereby affects the transport of thymidine into cells.
White to pale yellow powder
Soluble in methanol, ethanol, DMSO, or DMF
Caution: Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Light and moisture sensitive.
Formula:
C₃₉H₆₄N₄O₁₆ MW: 844.95 g/mol Storage Temperature: Refrigerator |
MDL Number:
MFCD00065709 CAS Number: 11089-65-9 UN: 3462 ADR: "6.1",III Merck Index: 14,9819 |
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