Anti-CD44 Rat Monoclonal Antibody (Biotin) [clone: IM7]

Supplier: Tonbo Biosciences

C57Bl/6 splenocytes were stained with 0.5 ug Biotin Anti-Hu/Mo CD44 (30-0441) (solid line) or 0.5 ug Biotin Rat IgG2b isotype control (dashed line), followed by Streptavidin PE.

C57Bl/6 splenocytes were stained with 0.5 ug Biotin Anti-Hu/Mo CD44 (30-0441) (solid line) or 0.5 ug Biotin Rat IgG2b isotype control (dashed line), followed by Streptavidin PE.

30-0441-U025 30-0441-U100

10208-340EA 27.5 USD

10208-340 10208-342

Anti-CD44 Rat Monoclonal Antibody (Biotin) [clone: IM7]

Antibodies

The IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organization, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or “standard” form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, through which it mediates adhesion.

The IM7 antibody may be used for detection of all isoforms of CD44, as it recognizes constant epitopes near the extracellular proximal domain. (Xu et al, 2002, J. Leukoc. Biol. 72:1133-1141). It has been reported to be cross-reactive with many non-human species including Baboon, Chimpanzee, Cynomolgus, Rhesus, Horse, Cow, Pig, Dog and Cat CD44.

Type: Primary
Antigen: CD44
Clonality: Monoclonal
Clone: IM7
Conjugation: Biotin
Epitope:
Host: Rat
Isotype: IgG2b kappa
Reactivity:

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