Anti-TNFSF4 Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: RM134L]

Supplier: Tonbo Biosciences

C57Bl/6 splenocytes were stimulated with anti-IgM and anti-CD40 for 4 days. Cells were then stained with 0.25 ug APC Anti-Mouse CD252 (20-5905) (solid line) or 0.25 ug APC Rat IgG2b isotype control (dashed line).

C57Bl/6 splenocytes were stimulated with anti-IgM and anti-CD40 for 4 days. Cells were then stained with 0.25 ug APC Anti-Mouse CD252 (20-5905) (solid line) or 0.25 ug APC Rat IgG2b isotype control (dashed line).

20-5905-U025 20-5905-U100

10210-118EA 66 USD

10210-118 10210-120

Anti-TNFSF4 Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: RM134L]

Antibodies

The RM134L antibody recognizes CD252, also known as OX-40 Ligand or CD134 Ligand, a member of the TNF superfamily that is present on the surface of antigen presenting cells and activated B lymphocytes. The OX-40 Ligand interacts with OX-40 (CD134) which is expressed primarily on activated T cells. This costimulatory interaction leads to increased proliferation and IL-2 production responses of activated T cells, and at the same time enhances proliferation and immunoglobulin secretion by activated B cells.

The RM134L antibody is useful for flow cytometric detection of CD252 on stimulated mouse splenocytes. It has also been reported to block the costimulatory activity of OX-40 Ligand. Please choose the appropriate format for each application.

Type: Primary
Antigen: TNFSF4
Clonality: Monoclonal
Clone: RM134L
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Rat
Isotype: IgG2b kappa
Reactivity: Mouse

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