TRIS HCl (tris(hydroxymethyl)aminomethane hydrochloride) ≥99%, Reagent Grade

Supplier: MP BIOMEDICALS (FKA ICN BIOMED

Synonyms: Tris(hydroxymethyl)aminomethane hydrochlorideTris(hydroxymethyl)methylamine hydrochlorideTrizma® hydrochlorideTromethane hydrochlorideTrizma(R) hydrochlorideTris(hydroxymethyl)methylammonium chlorideTHAM HClTris-HClTrometamol hydrochloride2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochlorideTRIS HCl

0210313001 0210313005 02103130.2 02103130.5 02103130.1
IC10313001EA 395.28 USD
IC10313001 IC103130.1 IC103130.2 IC10313005 IC103130.5
TRIS HCl (tris(hydroxymethyl)aminomethane hydrochloride) ≥99%, Reagent Grade
TRIS HCl (Tris-(hydroxymethyl) aminomethane hydrochloride)

Tris and Tris Hydrochloride have been useful as buffers in a wide variety of biological systems. Uses include pH control in vitro and in vivo for body fluids and in buffering systems for electrophoresis applications.


Tris has been used as a starting material for polymers, oxazolones (with carboxylic acids) and oxazolidines (with aldehydes). It can be used for the direct standardization of a strong acid solution; the equivalence point can be determined either potentiometrically or by use of a suitable indicator such as 3-(4-Dimethylamino-1-naphthylazo)-4-methoxybenzenesulfonic acid .


The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.

Formula: NH₂C(CH₂OH)₃·HCl
MW: 157.6 g/mol
MDL Number: MFCD00012590
CAS Number: 1185-53-1
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Specification Test Results

Synonyms Trometamol; Tromethamine; Tris-[hydroxymethyl]aminomethane; 2-Amino-2-(hydroxymethyl)-1,3-propanediol
Form White Crystalline Powder
Storage Store at Room Temperature (15 - 30 °C).
pH 4.0 - 5.0 (5% aq soln)
pka 8.08 (25 °C)

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