Cholesterol ≥99%, white powder
Supplier: MP BIOMEDICALS (FKA ICN BIOMED
Synonyms:
Cholesterin
, Cholest-5-en-3-ol
, (3Beta)-Cholest-5-en-3-ol
Cholesterol is a component used for the preparation and study of artificial model membranes. One example is a study of valinomycin induced changes in membrane potentials of red blood cell and phospholipid (phosphatidylcholine from egg yolk plus cholesterol) vesicle suspensions. Positively charged cyanine dyes were used that fluorimetrically respond to the change in potential. Cholesterol is suitable for use in liposome preparations. It is standard for clinical work.
Major component of all biological membranes; ~25% of total brain lipid is cholesterol.
Cholesterol monohydrate is practically insoluble in water (less then 0.5 mg/100 mL of water); slightly soluble in alcohol (1.29% w/w at 20 °C), more soluble in hot alcohol (100 g of saturated 96% alcoholic solution contains 28 g at 80 °C). Also one gram dissolves in 2.8 mL of ether, in 4.5 mL of chloroform, and in 1.5 mL of pyridine. The product is soluble in acetone, dioxane, ethyl acetate, benzene, petroleum ether, oils, fats, and in aqueous solutions of bile salts. Solutions should be protected from light.
Caution: Research Use Only (RUO).
Formula:
C₂₇H₄₆O MW: 386.66 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00003646 CAS Number: 57-88-5 |
Specification Test Results
Identity Test | Passes |
Purity | ≥99% |
Loss on Drying | ≤1.0% |
Optical Rotation | -34° to -42° |
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