Glycine ≥98%, powder
Supplier: MP BIOMEDICALS (FKA ICN BIOMED
Synonyms:
Aminoacetic acid
, H-Gly-OH
, Glycocoll
Glycine is a non-essential amino acid. Acts as an inhibitory neurotransmitter, particularly in brain stem and medulla. Shown to block NMDA-stimulated dopamine release in fetal mesencephalic cell cultures. Also reported to increase NMDA-receptor mediated synaptic potential in cortical neurons. It does not have a chiral center, so only amino acid with no asymmetric carbon. Therefore, it does not have a D- or L- isomer designation. This material is synthetic. It is the smallest of the 20 natural amino acids.
Glycine is commonly used as a component in Tris-glycine and Tris-glycine-SDS running buffers for polyacrylamide gel electrophoresis, a component of Towbin's transfer buffer for Western blots, a buffer substance in cryoenzymology, in osmotic pressure maintenance in isoelectric focusing of erythrocytes, salting-in effect in protein chemistry, and as a buffer component in the coupled phosphatase-kinase reaction for end labelling of restriction fragments. The growth requirements of various microorganisms is reported in the Handbook of Microbiology.
It is a non-chiral amino acid that can be synthesised in the body from the amino acid serine by Serine Hydroxy methyltransferase.
Soluble in water (250 mg/mL at 25 °C; 672 mg/mL at 100 °C); slightly soluble in alcohol and ethanol(95%); almost insoluble in ether.
Glycine is a non-essential amino acid. Acts as an inhibitory neurotransmitter, particularly in brain stem and medulla. Shown to block NMDA-stimulated dopamine release in fetal mesencephalic cell cultures. Also reported to increase NMDA-receptor mediated synaptic potential in cortical neurons. Glycine does not have a chiral center, so only amino acid with no asymmetric carbon. Therefore, it does not have a D- or L- isomer designation. This material is synthetic.It is the smallest of the 20 natural amino acids.
Formula:
NH₂CH₂COOH MW: 75.07 g/mol |
MDL Number:
MFCD00008131 CAS Number: 56-40-6 |
Specification Test Results
Synonyms | Aminoacetic acid; Gly; Aminoethanoic acid; Glycocoll |
Form | Powder |
Storage | Store at Room Temperature (15-30 °C). |
Isoelectric Point | 6.06 |
Loss on Drying | ≤0.5% |
pka | for the α carboxyl group: 2.35; and for the α amino group: 9.78 at 25 °C |
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