Puromycin dihydrochloride

Supplier: MP BIOMEDICALS (FKA ICN BIOMED

Synonyms: (S)-2-Amino-N-((2S,3S,4R,5R)-5-(6-(Dimethylamino)-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)-3-(4-methoxyphenyl)propanamide dihydrochloride

0210055210 0210055225

IC10055210EA 50.59 USD

IC10055210 IC10055225

Puromycin dihydrochloride

Puromycin dihydrochloride

Puromycin dihydrochloride is a part of the amino-nucleoside family of antibiotics and is derived from Streptomyces alboniger.

Off-white Powder

Puromycin's biological activity are antitumor effect, nephrotoxic action, inhibition of purine and/or protein synthesis and antitrypanosome activity. It inhibits protein synthesis by causing premature chain termination acting as an analog of the 3′-terminal end of the aminoacyl-tRNA. Prevents growth of bacteria, protozoa, algae, and mammalian cells.

Extinction coefficients: 20.3 (275 nm, 0.1 N NaOH), 19.5 (268 nm, 0.1 NHCl) (Lit.)

Soluble in water

Specification Test Results

Source

Streptomyces albo-niger

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