Anti-AIM2 Mouse Monoclonal Antibody [clone: 3B10]

Supplier: AdipoGen Life Sciences
AG-20B-0040-C100
102514-350EA 443.08 USD
102514-350
Anti-AIM2 Mouse Monoclonal Antibody [clone: 3B10]
Antibodies
AIM2 is a strong candidate as a tumor suppressor as it is a member of the HIN-200 (hemopoietic interferon-inducible, nuclear proteins containing a 200 amino acid repeat) family of proteins that have been shown to regulate cell growth and survival. The HIN-200 family of proteins consists of four members in human, IFI 16, MNDA, AIM2 and IFIXl. Recently it has been reported that AIM2 is a receptor for cytosolic dsDNA, which forms a novel inflammasome complex with ASC to activate caspase-1-mediated processing of IL-1beta.

  • Stable for at least 1 year after receipt when stored at -20°C.

Purified from concentrated hybridoma tissue culture supernatant.

Purity: >95% (SDS-PAGE)

Type:
Antigen: AIM2
Clonality: Monoclonal
Clone: 3B10
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
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