N-Acetyl-L-cysteine
Supplier: BACHEM AMERICAS INC
Sequence: Ac-Cys-OH
Synonym(s): NAC
NAC induced apoptosis in rat and human smooth muscle cells and serves as an efficient substrate for the rat liver microsomal glutathione transferase with 1-chloro-2,4-dinitrobenzene as second substrate. The conjugate with phenethyl isothiocyanate induces apoptosis predominantly in growth-promoted cells, which leads to the assumption that this conjugate inhibits lung carcinogenesis. Furthermore, NAC has been found to act as a specific inhibitor of TGF-β signaling targeting different components of the TGF-β signaling machinery. Bachem also offers the dimer of NAC, DiNAC (E-2965).
Formula:
C₅H₉NO₃S Storage Temperature: Ambient |
MDL Number:
MFCD00004880 CAS Number: 616-91-1 |
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