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Description: 6-((6-(1-Methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)thio)quinoline, Purity: 98+%, CAS Number: 1022150-57-7, Appearance: Solid, Storage: Sealed in dry, Store in freezer, under -20 C, Size: 50mg
Catalog Number: 77685-752
Supplier: Ambeed

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Description: SGX523 is an ATP-competitive, triazolopyridazine-based inhibitor of MET at an IC(50) of 4nM. SGX523 has higher affinity for the unphosphorylated form of MET (Ki = 2.7nM) than the more active phospho-enzyme (Ki = 23nM). In a broad panel of 213 kinases, SGX523 was extremely selective, with no inhibition >36%, suggesting IC(50) values > 1µM, including the closely-associated RON kinase.
Catalog Number: 102992-420
Supplier: Adipogen


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