Anti-DDX3X Rabbit Polyclonal Antibody

Supplier: ProSci

Western blot analysis of DDX3 in HepG2 cell lysate with DDX3 antibody at (A) 1 and (B) 2 ug/mL.

Immunocytochemistry of DDX3 in HepG2 cells with DDX3 antibody at 10 µg/ml.

Western blot analysis of DDX3 in HepG2 cell lysate with DDX3 antibody at (A) 1 and (B) 2 ug/mL.

Immunocytochemistry of DDX3 in HepG2 cells with DDX3 antibody at 10 µg/ml.

3759_S

10748-552EA 185.25 USD

10748-552

Anti-DDX3X Rabbit Polyclonal Antibody

Antibodies

DDX3 Antibody: DDX3 contains all of the motifs of the DEAD-box family of RNA helicases, including the Asp-Glu-Ala-Asp sequence that gives the protein family its name and distinguishes it from other RNA helicases. DDX3 is localized to the X chromosome and has a highly conserved functional homolog (DBY) on the Y chromosome. DDX3 is thought to be involved in RNA splicing, RNA transport, and translation initiation. It has also been shown to be involved in cell growth control and is deregulated in hepatitis virus-associated hepatocellular carcinoma. Recent experiments suppressing DDX3 expression blocked HIV-1 RNA export from the nucleus, suggesting that DDX3 functions as a shuttling protein that transports the HIV-1 protein Rev and its cofactor CRM1 from the nucleus to the cytoplasm.

Type: Primary
Antigen: DDX3X
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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