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Image Unavailable-89158-030

17-AAG ≥98% (by TLC)

Catalog Number: (89158-030)
Supplier: Enzo Life Sciences
Description: HSP90 inhibitor
Product Image-76344-648

17-AAG

Supplier: RPI
Description: 17-AAG (17-Allylamino-17-demethoxygeldanamycin) is a synthetic derivative of geldanamycin. Like geldanamycin, 17-AAG is recognised for its role as an inhibitor of heat shock protein 90 (Hsp90), a molecular chaperone involved in protein folding and stabilisation.

Image Unavailable-AAJ66960-MC

17-AAG 99%

Supplier: Thermo Scientific Chemicals
Description: 17-(Allylamino)-17-demethoxygeldanamycin (17-AAG) inhibits heat shock protein 90 (Hsp90), the expression of heat shock factor-1, and the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2

SDS Certificates

Image Unavailable-ALA126970-5MG

17-AAG ≥98%

Catalog Number: (ALA126970-5MG)
Supplier: ALADDIN SCIENTIFIC
Description: 17-AAG (Tanespimycin) is a potent HSP90 inhibitor with IC50 of 5 nM, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells.A potent Hsp90 inhibitor for tumor cells

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Image Unavailable-77192-880

17-AAG 98%

Supplier: Ambeed
Description: (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate, Purity: 98%, CAS Number: 75747-14-7, Appearance: Form: solid, Storage: Store in freezer, under -20 C, Size: 1mg

Image Unavailable-102125-504

17-AAG (synthetic)

Catalog Number: (102125-504)
Supplier: Novus Biologicals
Description: Glendanamycin (GA), a benzoquinone ansamycin antibiotic, interferes with the action of Hsp90 leading to degradation of Hsp90 client proteins. GA itself however has undesirable properties such as poor aqueous solubility and liver toxicity; therefore, numerous analogs have been synthesized, such as 17-AAG. 17-AAG is an HSP-90 inhibitor that displays a 100-fold higher affinity for HSP-90 derived from tumor cells compared to HSP-90 from normal cells. 17-AAG inhibits Akt activation and expression in tumors and synergizes with a number of antitumor agents such as taxol, cisplatin and UCN-01 (400 nM 17-AAG, U937 cells).
Image Unavailable-102513-636

17-AAG ≥98% (by HPLC)

Supplier: Adipogen
Description: Potent, less toxic analog of geldanamycin (Prod. No. BVT-0196). Inhibits the essential ATPase activity of HSP90. Telomerase activity inhibitor. Apoptosis inducer. Antitumor compound.

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